Which of the following is a larger blister containing a watery fluid?

A larger blister containing a watery fluid is referred to as a bulla. The term "bulla" describes a raised lesion on the skin that typically measures more than 5 millimeters in diameter and is filled with clear fluid. This distinguishes it from other types of skin lesions, such as vesicles, which are smaller (typically less than 5 millimeters) and also contain fluid but are not classified as "large" blisters.

In contrast, a macule is a flat, distinguishable, discolored area of skin that does not involve any change in texture or elevation, thus not resembling a blister at all. A pustule refers to a small, raised lesion filled with pus, indicative of infection or inflammation, and is also not a watery blister but rather a more opaque fluid. Therefore, the definition and characteristics of a bulla make it the appropriate choice for identifying a larger blister containing watery fluid.